Which heart chamber is least important

Too much heart can be dangerous

According to a press release by the DMW, one in 500 people has a hereditary predisposition for the pathological enlargement of the heart muscle. The genetic errors usually affect the sarcomere, the functional units in the muscle fibers in which proteins shift against each other and thus contract the muscle. Numerous mutations have been discovered in recent years, and specialized laboratories now find 60 to 70 percent of the cause of hypertrophic cardiomyopathy when patients come from families with multiple affected members, reports Professor Dr. Nobert Frey, Director at the Clinic for Cardiology and Angiology at the University Medical Center Schleswig-Holstein in Kiel (doi: 10.1055 / s-0032-1332958). If the disease does not occur in families, the rate is 10 to 50 percent. Very few patients are aware of their genetic disease when they seek treatment. Symptoms are often a painful tightness in the chest, angina pectoris, or shortness of breath, which are otherwise very unusual in young people. Some patients also experience brief "dropouts" of the heart, which are accompanied by a brief fainting. Early diagnosis of the disease is important because the enlargement can throw the heart out of sync. According to Frey, sudden cardiac death is the most common cause of death in symptom-free patients before the age of 35.